منابع مشابه
Pathologies Associated with Serum IgG4 Elevation
Statement of Purpose. IgG4-related disease (IgG4-RD) is usually associated to an increase of serum IgG4 levels. However other conditions have also been associated to high serum IgG4 levels. Methods. All IgG subclasses analyses performed in our hospital over a one-year period were analyzed. When IgG4 level were over 1.35 g/L, the patient's clinical observation was analyzed and both final diagnos...
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quired abnormalities of megakaryocyte production that could be due to progenitor trapping in the osteoblastic niche? There are elegant techniques available for in vivo microscopy of the marrow space in living animals that could be used to study these questions4 and I am confident that these experiments will be or are being done. I look forward to more details regarding the movement of megakaryo...
متن کاملAn Audit of the Pathologies Associated with Impacted Wisdom Teeth
The purpose of this study was to find out the types of pathologies that can arise in association with impacted wisdom teeth. Two hundred consecutive patients scheduled for extraction of one or more of their impacted wisdom teeth were evaluated clinically and radiographically. Orthopantogram (OPG) was the standard radiograph. 194 (97 %) of the teeth were associated with pathologies. Pericoroniti...
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In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.
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The p53 protein exhibits high binding affinity to its response elements (RE) associated with cell cycle arrest (CCAsites), but relatively low affinity to the RE associated with apoptosis (Apo-sites). To examine whether the long-range genomic environment of the RE is relevant to the differential p53-DNA binding, we analyzed 22 experimentally validated RE including 15 Apo-sites and 7 CCA-sites. T...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2010
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a001180